Lansoprazole sodium
Based on 5 publication(s) in Google Scholar
Lansoprazole sodium (AG 1749 sodium) is an orally active proton pump inhibitor which prevents the stomach from producing acid. Lansoprazole sodium (AG 1749 sodium) is a potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor (exosome inhibitor).
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- Pureté: 98.80%
- CAS No.: 226904-00-3
- Formule: C16H13F3N3NaO2S
- Masse moléculaire:391.34
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Stockage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Pureté et documentation
- Références
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Help & FAQs
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HY-B0656
Rabeprazole
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HY-13662
Lansoprazole
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HY-B0656A
Rabeprazole sodium
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HY-17023
Esomeprazole sodium
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HY-17507
Pantoprazole
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HY-100558
Bafilomycin A1
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HY-B1446
Esomeprazole magnesium
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HY-B0572
Zinc Pyrithione
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HY-17421
Tenatoprazole
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HY-17022
Esomeprazole magnesium trihydrate
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HY-101664
Ilaprazole
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HY-B0656R
Rabeprazole (Standard)
Publications Citing Use of MedChemExpress (MCE) Lansoprazole sodium
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Customer Validation & Images
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Bio/Physico-chemical Assay
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Bio/Physico-chemical Assay
Voir tous les produits spécifiques à Isoform Phospholipase
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Activité biologique
| NCT Number | Sponsor | Condition | Start Date |
Phase
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|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 226904-00-3
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Appearance Solid
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Masse moléculaire 391.34
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Formule C16H13F3N3NaO2S
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Color White to off-white
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SMILES
O=S(C1=NC2=CC=CC=C2[N-]1)CC3=NC=CC(OCC(F)(F)F)=C3C.[Na+]
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Synonyms
AG-1749 sodium
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (5)
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Journal Impact Factor
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Most Recent
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Nat Commun
2023 Jul 14;14(1):4217. PMID: 37452028 -
J Med Chem
Mechanism of CRM1 Inhibition by Lansoprazole and Its Synergy with Cisplatin in Gastric Cancer. [Abstract]2026 May 28;69(10):11705-11719. PMID: 42134807 -
Lansoprazole sodium purchased from MedChemExpress. Usage Cited in: Results Chem. 2024 Oct.
Zero-order absorption spectra of 5.0 µg/mL (LEV, RAB, LAN (Lansoprazole), PAR, and AMO).
Lansoprazole sodium purchased from MedChemExpress. Usage Cited in: Results Chem. 2024 Oct.
Determination of LEV, RAB, Lansoprazole (LAN), PAR, and AMO in the pharmaceutical formulation by chemometric techniques and application of the standard addition technique.
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Sci Rep
2026 Mar 20;16(1):14300. PMID: 41862552 -
FASEB J
Lansoprazole Enhances Everolimus Efficacy Through DDIT3-Mediated PI3K/AKT/mTOR Pathway Inhibition in Pancreatic Neuroendocrine Neoplasms Proliferation. [Abstract]2026 Apr 15;40(7):e71722. PMID: 41911054
Solvant et solubilité
DMSO : 125 mg/mL (319.42 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (272 KB)
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SDS (254 KB)
- English - EN (254 KB)
- Français - FR (254 KB)
- Deutsch - DE (254 KB)
- Norwegian - NO (254 KB)
- Español - ES (254 KB)
- Swedish - SV (254 KB)
- Italian - IT (254 KB)
- Korean - KR (254 KB)
- Portuguese - PT (254 KB)
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Instruction de manipulation (2659 KB)
Références
[1]. Kokufu, T., et al., Effects of lansoprazole on pharmacokinetics and metabolism of theophylline. Eur J Clin Pharmacol, 1995. 48(5): p. 391-5. [Content Brief]
[2]. Huarui Zhang, et al. Advances in the discovery of exosome inhibitors in cancer. J Enzyme Inhib Med Chem. 2020 Dec;35(1):1322-1330. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.5553 mL | 12.7766 mL | 25.5532 mL | 63.8831 mL |
| 5 mM | 0.5111 mL | 2.5553 mL | 5.1106 mL | 12.7766 mL | |
| 10 mM | 0.2555 mL | 1.2777 mL | 2.5553 mL | 6.3883 mL | |
| 15 mM | 0.1704 mL | 0.8518 mL | 1.7035 mL | 4.2589 mL | |
| 20 mM | 0.1278 mL | 0.6388 mL | 1.2777 mL | 3.1942 mL | |
| 25 mM | 0.1022 mL | 0.5111 mL | 1.0221 mL | 2.5553 mL | |
| 30 mM | 0.0852 mL | 0.4259 mL | 0.8518 mL | 2.1294 mL | |
| 40 mM | 0.0639 mL | 0.3194 mL | 0.6388 mL | 1.5971 mL | |
| 50 mM | 0.0511 mL | 0.2555 mL | 0.5111 mL | 1.2777 mL | |
| 60 mM | 0.0426 mL | 0.2129 mL | 0.4259 mL | 1.0647 mL | |
| 80 mM | 0.0319 mL | 0.1597 mL | 0.3194 mL | 0.7985 mL | |
| 100 mM | 0.0256 mL | 0.1278 mL | 0.2555 mL | 0.6388 mL |
Lansoprazole sodium Related Classifications
HY-13662A Related Classifications
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