Calcifediol-d9
Calcifediol-d9 (25-hydroxy Vitamin D3-d9) is the deuterium labeled Calcifediol (HY-32351). Calcifediol (25-hydroxy Vitamin D3) is an effective VDR ligand and VD supplement. Calcifediol is a prohormone of the vitamin D endocrine system (VDES) and is hydroxylated in the liver to produce the active form, calcitriol. Calcifediol can rapidly increase serum VD levels.
For research use only. We do not sell to patients.
- CAS No.: 1539301-45-5
- Formula: C27H35D9O2
- Molecular Weight:409.69
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All Endogenous Metabolite Isoforms
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Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 1539301-45-5
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Unlabeled Cas 19356-17-3
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Molecular Weight 409.69
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Formula C27H35D9O2
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SMILES
C=C(CC[C@@H](C/1)O)C1=C/C=C(CCC2)/[C@@](CC[C@]3([H])[C@H](C)CCCC(C([2H])([2H])[2H])(O)C([2H])([2H])[2H])([H])[C@]23C([2H])([2H])[2H]
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Synonyms
25-hydroxy Vitamin D3-d9
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Castoldi A, et al. Calcifediol-loaded liposomes for local treatment of pulmonary bacterial infections. Eur J Pharm Biopharm. 2016 Nov 22. [Content Brief]
[2]. Wei Zheng, et al. Vitamin D-induced vitamin D receptor expression induces tamoxifen sensitivity in MCF-7 stem cells via suppression of Wnt/β-catenin signaling. Biosci Rep. 2018 Dec 7;38(6):BSR20180595. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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