100510-33-6
Chemical Structure
Adibendan
Synonym(s): BM 14478
- CAS No.: 100510-33-6
- Formula:C16H14N4O
- Molecular Weight:278.31
IUPAC Name: 7,7-dimethyl-2-(pyridin-4-yl)-5,7-dihydroimidazo[4,5-f]indol-6(1H)-one
InChIKey: TVLQBBHUNDMTEC-UHFFFAOYSA-N
SMILES: O=C1NC2=CC3=C(C=C2C1(C)C)NC(C4=CC=NC=C4)=N3
Biological Activity: Adibendan (BM 14478), a benzimidazole derivative, is an orally active, selective phosphodiesterase III (PDE III) activity inhibitor (IC50=2.0 μM). Adibendan has IC50 values more than 60-fold higher for the inhibition of PDE I or II. Adibendan is a new cardiotonic agent[1].
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Adibendan | Adibendan (BM 14478), a benzimidazole derivative, is an orally active, selective phosphodiesterase III (PDE III) activity inhibitor (IC50=2.0 μM). Adibendan has IC50 values more than 60-fold higher for the inhibition of PDE I or II. Adibendan is a new cardiotonic agent. | |||||||||||||||||||||
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Keywords