1025400-45-6
1025400-45-6
Chemical Structure
LP10
- No. CAS: 1025400-45-6
- Formula:C24H28N4O2
- Molecular Weight:404.50
IUPAC Name: N-(3-(1H-indol-3-yl)-1-oxo-1-(pyridin-4-ylamino)propan-2-yl)-4-methylcyclohexane-1-carboxamide
InChIKey: ICFUCABJWQGTGU-UHFFFAOYSA-N
SMILES: O=C(C(CC1=CNC2=C1C=CC=C2)NC(C3CCC(CC3)C)=O)NC4=CC=NC=C4
Biological Activity: LP10 is a non-azole CYP51 inhibitor with activity against Trypanosoma cruzi infection. Treatment with LP10 blocks the 14α-demethylation step, leading to disruption of the parasite cell membrane and ultimately triggering the death of important clinically relevant amoeba stages[1].
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LP10 | LP10 is a non-azole CYP51 inhibitor with activity against Trypanosoma cruzi infection. Treatment with LP10 blocks the 14α-demethylation step, leading to disruption of the parasite cell membrane and ultimately triggering the death of important clinically relevant amoeba stages. | |||||||||||||||||||||
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References
Keywords
