1030612-90-8
1030612-90-8
Chemical Structure
MK-8245
- CAS No.: 1030612-90-8
- Formula:C17H16BrFN6O4
- Molecular Weight:467.25
IUPAC Name: 2-(5-(3-(4-(2-bromo-5-fluorophenoxy)piperidin-1-yl)isoxazol-5-yl)-2H-tetrazol-2-yl)acetic acid
InChIKey: UJEAABFSXKCSGI-UHFFFAOYSA-N
SMILES: O=C(CN1N=C(N=N1)C2=CC(N3CCC(CC3)OC4=CC(F)=CC=C4Br)=NO2)O
Biological Activity: MK-8245 is a potent, liver-targeted stearoyl-CoA desaturase (SCD) inhibitor, with IC50s of 1 nM for human SCD1 and 3 nM for both rat SCD1 and mouse SCD1, with antidiabetic and antidyslipidemic efficacy[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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MK-8245 | 99.04% | MK-8245 is a potent, liver-targeted stearoyl-CoA desaturase (SCD) inhibitor, with IC50s of 1 nM for human SCD1 and 3 nM for both rat SCD1 and mouse SCD1, with antidiabetic and antidyslipidemic efficacy. | ||||||||||||||||||||
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References
Keywords
