1032754-81-6

GNE-477 Chemical Structure
1032754-81-6

Chemical Structure

GNE-477

  • CAS No.: 1032754-81-6
  • Formula:C21H28N8O3S2
  • Molecular Weight:504.63

IUPAC Name: 5-(7-methyl-6-((4-(methylsulfonyl)piperazin-1-yl)methyl)-4-morpholinothieno[3,2-d]pyrimidin-2-yl)pyrimidin-2-amine

InChIKey: AKKCGLXULFRAET-UHFFFAOYSA-N

SMILES: NC1=NC=C(C2=NC(N3CCOCC3)=C4C(C(C)=C(CN5CCN(S(=O)(C)=O)CC5)S4)=N2)C=N1

Biological Activity: GNE-477 is a potent and efficacious dual PI3K (IC50=4 nM)/mTOR(Ki=21 nM) inhibitor.

Cat. No. Product Name Purity Description Pricing
HY-11042 		GNE-477 98.75% GNE-477 is a potent and efficacious dual PI3K (IC50=4 nM)/mTOR(Ki=21 nM) inhibitor.
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