103361-09-7
Chemical Structure
Flumioxazin
Synonym(s): V-53482
- CAS No.: 103361-09-7
- Formula:C19H15FN2O4
- Molecular Weight:354.33
IUPAC Name: 2-(7-fluoro-3-oxo-4-(prop-2-yn-1-yl)-3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl)-4,5,6,7-tetrahydro-1H-isoindole-1,3(2H)-dione
InChIKey: FOUWCSDKDDHKQP-UHFFFAOYSA-N
SMILES: O=C1N(C2=C(F)C=C(OCC(N3CC#C)=O)C3=C2)C(C4=C1CCCC4)=O
Biological Activity: Flumioxazin (V-53482) is a protoporphyrinogen IX oxidase (PPO) inhibitor with a rat target IC50 of 4.58 nM. Flumioxazin is found in its biological sources and is used for pre-emergence control of dicotyledonous weeds in soybean and peanut. Flumioxazin inhibits protoporphyrinogen oxidase, blocking chlorophyll and heme biosynthesis, leading to protoporphyrin IX accumulation, oxidative stress, membrane damage, and cell death. Flumioxazin is used in research on weed control[1][2][3].
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Flumioxazin | 99.13% | Flumioxazin (V-53482) is a protoporphyrinogen IX oxidase (PPO) inhibitor with a rat target IC50 of 4.58 nM. Flumioxazin is found in its biological sources and is used for pre-emergence control of dicotyledonous weeds in soybean and peanut. Flumioxazin inhibits protoporphyrinogen oxidase, blocking chlorophyll and heme biosynthesis, leading to protoporphyrin IX accumulation, oxidative stress, membrane damage, and cell death. Flumioxazin is used in research on weed control. | ||||||||||||||||||||
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Flumioxazin (Standard) | ≥98% | Flumioxazin (Standard) (V-53482 (Standard)) is the analytical standard of Flumioxazin (HY-114507). This product is intended for research and analytical applications. Flumioxazin (V-53482) is a protoporphyrinogen IX oxidase (PPO) inhibitor with a rat target IC50 of 4.58 nM. Flumioxazin is found in its biological sources and is used for pre-emergence control of dicotyledonous weeds in soybean and peanut. Flumioxazin inhibits protoporphyrinogen oxidase, blocking chlorophyll and heme biosynthesis, leading to protoporphyrin IX accumulation, oxidative stress, membrane damage, and cell death. Flumioxazin is used in research on weed control. | ||||||||||||||||||||
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References
- [1]. Oliveira TF, et al. Ecogenotoxicity of a flumioxazin-based herbicide in terrestrial plants. Journal of toxicology and environmental health. Part A. 2026;89(6):251-265.
- [2]. Iwashita K, et al. Flumioxazin, a PPO inhibitor: A weight-of-evidence consideration of its mode of action as a developmental toxicant in the rat and its relevance to humans. Toxicology. 2022 Apr 30;472:153160.
- [3]. Ferrell JA, et al. Flumioxazin soil persistence and mineralization in laboratory experiments. Journal of agricultural and food chemistry. 2003 Jul 30;51(16):4719-21. [Content Brief]
