1063331-94-1
Chemical Structure
NS13001
- CAS No.: 1063331-94-1
- Formula:C17H16ClN7
- Molecular Weight:353.81
IUPAC Name: N-(4-chlorophenyl)-2-(3,5-dimethyl-1H-pyrazol-1-yl)-9-methyl-9H-purin-6-amine
InChIKey: DVQOPNIPUIOXHU-UHFFFAOYSA-N
SMILES: CN1C=NC2=C(NC3=CC=C(Cl)C=C3)N=C(N4N=C(C)C=C4C)N=C12
Biological Activity: NS13001 is a potent, selective, orally active allosteric positive modulator of SK channels (small conductance calcium-activated potassium channels). The EC50s are 1.8 and 0.14 μM for SK2 and SK3, respectively. NS13001 holds promise as a potential therapeutic agent for treatment of spinocerebellar ataxia type 2 (SCA2) and possibly other cerebellar ataxias[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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NS13001 | 99.62% | NS13001 is a potent, selective, orally active allosteric positive modulator of SK channels (small conductance calcium-activated potassium channels). The EC50s are 1.8 and 0.14 μM for SK2 and SK3, respectively. NS13001 holds promise as a potential therapeutic agent for treatment of spinocerebellar ataxia type 2 (SCA2) and possibly other cerebellar ataxias. | ||||||||||||||||||||
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Keywords
