1065581-69-2
Chemical Structure
CBP/p300-IN-21
- CAS No.: 1065581-69-2
- Formula:C19H16ClNO4
- Molecular Weight:357.79
InChIKey: LEZRKXQEEAZRPS-UHFFFAOYSA-N
SMILES: OC(C(OC)=C1)=CC(C1=C2)=CC3=[N+]2CCC4=CC(OCO5)=C5C=C43.[Cl-]
Biological Activity: CBP/p300-IN-21 (Compound 5d) is a selective CBP/p300 inhibitor (IC50: 0.07 and 1.755 μM for p300 and CBP). CBP/p300-IN-21 decreases H3K18Ac level. CBP/p300-IN-21 inhibits growth of 4T1 tumor growth in mice[1].
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CBP/p300-IN-21 | CBP/p300-IN-21 (Compound 5d) is a selective CBP/p300 inhibitor (IC50: 0.07 and 1.755 μM for p300 and CBP). CBP/p300-IN-21 decreases H3K18Ac level. CBP/p300-IN-21 inhibits growth of 4T1 tumor growth in mice. | |||||||||||||||||||||
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Keywords