1073529-41-5
Chemical Structure
ABL127
- CAS No.: 1073529-41-5
- Formula:C17H20N2O5
- Molecular Weight:332.35
IUPAC Name: dimethyl (R)-3-cyclopentyl-4-oxo-3-phenyl-1,2-diazetidine-1,2-dicarboxylate
InChIKey: ZRHWCAFAIHTQKD-KRWDZBQOSA-N
SMILES: O=C(N1N(C(OC)=O)[C@@](C2=CC=CC=C2)(C3CCCC3)C1=O)OC
Biological Activity: ABL127 is a selective and covalent inhibitor of protein methylesterase 1 (PME-1) with IC50s of 6.4 nM and 4.2 nM in HEK293T and MDA-MB-231 cells, respectively.
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ABL127 | 99.6% | ABL127 is a selective and covalent inhibitor of protein methylesterase 1 (PME-1) with IC50s of 6.4 nM and 4.2 nM in HEK293T and MDA-MB-231 cells, respectively. | ||||||||||||||||||||
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Keywords