1082058-99-8
Chemical Structure
TUG-424
- CAS No.: 1082058-99-8
- Formula:C18H16O2
- Molecular Weight:264.32
IUPAC Name: 3-(4-(o-tolylethynyl)phenyl)propanoic acid
InChIKey: FODHWOBAQBTTFS-UHFFFAOYSA-N
SMILES: OC(CCC(C=C1)=CC=C1C#CC2=C(C)C=CC=C2)=O
Biological Activity: TUG-424 is a potent and selective free fatty acid receptor 1 (FFA1/GPR40) agonist with an EC50 of 32 nM. TUG-424 significantly increases glucose-stimulated insulin secretion at 100 nM. TUG-424 may serve to explore the role of FFA1 in metabolic diseases such as diabetes or obesity[1]. TUG-424 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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TUG-424 | 99.68% | TUG-424 is a potent and selective free fatty acid receptor 1 (FFA1/GPR40) agonist with an EC50 of 32 nM. TUG-424 significantly increases glucose-stimulated insulin secretion at 100 nM. TUG-424 may serve to explore the role of FFA1 in metabolic diseases such as diabetes or obesity. TUG-424 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | ||||||||||||||||||||
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Keywords
