108427-72-1
108427-72-1
Chemical Structure
AS-35
- CAS No.: 108427-72-1
- Formula:C21H20N6O4
- Molecular Weight:420.42
IUPAC Name: 9-((4-acetyl-3-hydroxy-2-propylphenoxy)methyl)-3-(1H-tetrazol-5-yl)-4H-pyrido[1,2-a]pyrimidin-4-one
InChIKey: RVRGDCZGEKSIRW-UHFFFAOYSA-N
SMILES: O=C1C(C2=NN=NN2)=CN=C3N1C=CC=C3COC4=CC=C(C(C)=O)C(O)=C4CCC
Biological Activity: AS-35 is an orally effective, potent and selective antagonist of leukotrienes, antagonizes LTC4-, LTD4 and LTE4-induced contractions of the ileum with IC50 values of 8 nM, 4 nM and 3 nM, respectively, and has antiallergic activities.
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AS-35 | AS-35 is an orally effective, potent and selective antagonist of leukotrienes, antagonizes LTC4-, LTD4 and LTE4-induced contractions of the ileum with IC50 values of 8 nM, 4 nM and 3 nM, respectively, and has antiallergic activities. | |||||||||||||||||||||
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Keywords
