109304-06-5
109304-06-5
Chemical Structure
2’-Deoxy-2’-fluoroarabino-O6-methyl inosine
- CAS No.: 109304-06-5
- Formula:C11H13FN4O4
- Molecular Weight:284.24
IUPAC Name: (2R,3R,4R,5R)-4-fluoro-2-(hydroxymethyl)-5-(6-methoxy-9H-purin-9-yl)tetrahydrofuran-3-ol
InChIKey: BQLCZDLJTPAFTK-HUKYDQBMSA-N
SMILES: O[C@H]1[C@@H](F)[C@H](N(C=N2)C3=C2C(OC)=NC=N3)O[C@@H]1CO
Biological Activity: 2’-Deoxy-2’-fluoroarabino-O6-methyl inosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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2’-Deoxy-2’-fluoroarabino-O6-methyl inosine | 2’-Deoxy-2’-fluoroarabino-O6-methyl inosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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References
