109333-26-8
109333-26-8
Chemical Structure
NPC-567
- CAS No.: 109333-26-8
- Formula:C60H87N19O13
- Molecular Weight:1282.45
InChIKey: RBIXVHPHNGXTCI-QJTYZATASA-N
SMILES: O=C(N[C@H](CC1=CC=CC=C1)C(N[C@H](C(N[C@H](C(O)=O)CCCNC(N)=N)=O)CC2=CC=CC=C2)=O)[C@H](CO)NC([C@@H](NC(CNC([C@H]3N(C([C@H]4N(C([C@@H](NC([C@H](N)CCCNC(N)=N)=O)CCCNC(N)=N)=O)CCC4)=O)C[C@H](O)C3)=O)=O)CC5=CC=CC=C5)=O
Biological Activity: NPC-567 is a bradykinin B2 receptor antagonist. NPC-567 is effective in inhibiting the acute response to allergen in the airways[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
NPC-567 | NPC-567 is a bradykinin B2 receptor antagonist. NPC-567 is effective in inhibiting the acute response to allergen in the airways. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
- [1]. Cheronis JC, et al. A new class of bradykinin antagonists: synthesis and in vitro activity of bissuccinimidoalkane peptide dimers. J Med Chem. 1992 May 1;35(9):1563-72. [Content Brief]
- [2]. Sylvin H, et al. The effect of a bradykinin B2 receptor antagonist, NPC-567, on allergen-induced airway responses in a porcine model. Inflamm Res. 2001 Sep;50(9):453-9. [Content Brief]
Keywords
