1098233-10-3
Chemical Structure
3’-O-MOE-5Me-C(Bz)-2’-phosphoramidite
- CAS 番号: 1098233-10-3
- Formula:C50H62N5O10P
- Molecular Weight:924.03
IUPAC Name: (2R,3R,4R,5R)-2-(4-benzamido-5-methyl-2-oxo-3,4-dihydropyrimidin-1(2H)-yl)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(2-methoxyethoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChIKey: ANDNEYHUAGYMNQ-YLUVQPHQSA-N
SMILES: COC(C=C1)=CC=C1C(C2=CC=C(OC)C=C2)(C3=CC=CC=C3)OC[C@H]4O[C@@H](N5C(NC(NC(C6=CC=CC=C6)=O)C(C)=C5)=O)[C@H](OP(OCCC#N)N(C(C)C)C(C)C)[C@@H]4OCCOC
Biological Activity: 3’-O-MOE-5Me-C(Bz)-2’-phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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3’-O-MOE-5Me-C(Bz)-2’-phosphoramidite | 3’-O-MOE-5Me-C(Bz)-2’-phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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