1124381-43-6
1124381-43-6
Chemical Structure
MSC 2032964A
- CAS No.: 1124381-43-6
- Formula:C16H13F3N6O
- Molecular Weight:362.31
IUPAC Name: N-(5-(cyclopropylamino)-7-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl)nicotinamide
InChIKey: XUKGFHHTSUKORV-UHFFFAOYSA-N
SMILES: O=C(C1=CC=CN=C1)NC2=NN3C(NC4CC4)=CC(C(F)(F)F)=CC3=N2
Biological Activity: MSC 2032964A is an orally active, selective inhibitor for apoptosis signal-regulating kinase 1(ASK1) with IC50 of 96 nM. MSC 2032964A preserves the visual responses in EAE mice model and exhibits potency in ameliorating the neuroinflammation[1].
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MSC 2032964A | MSC 2032964A is an orally active, selective inhibitor for apoptosis signal-regulating kinase 1(ASK1) with IC50 of 96 nM. MSC 2032964A preserves the visual responses in EAE mice model and exhibits potency in ameliorating the neuroinflammation. | |||||||||||||||||||||
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References
Keywords
