1134188-26-3
1134188-26-3
Chemical Structure
Epimagnolin B
- CAS No.: 1134188-26-3
- Formula:C23H28O7
- Molecular Weight:416.46
IUPAC Name: (1R,3aR,4S,6aR)-1-(3,5-dimethoxyphenyl)-4-(3,4,5-trimethoxyphenyl)tetrahydro-1H,3H-furo[3,4-c]furan
InChIKey: DTZKTJXOROSTPI-YHDSQAASSA-N
SMILES: COC1=C(OC)C(OC)=CC([C@@H]2[C@]3([H])[C@]([C@H](C4=CC(OC)=CC(OC)=C4)OC3)([H])CO2)=C1
Biological Activity: Epimagnolin B is a bisepoxylignan isolated from Magnolia fargesii, with anti-inflammatory activity and antiallergic effects. Epimagnolin B inhibits NO production in LPS-activated microglia. Epimagnolin B exhibited antiallergic effects[1][2].
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Epimagnolin B | Epimagnolin B is a bisepoxylignan isolated from Magnolia fargesii, with anti-inflammatory activity and antiallergic effects. Epimagnolin B inhibits NO production in LPS-activated microglia. Epimagnolin B exhibited antiallergic effects. | |||||||||||||||||||||
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References
- [1]. Kim JY, et al. In vitro anti-inflammatory activity of lignans isolated from Magnolia fargesii. Bioorg Med Chem Lett. 2009 Feb 1;19(3):937-40. [Content Brief]
- [2]. Xing Zhang, et al. Bioassay-guided isolation of bisepoxylignans from the flower buds of Magnolia biondii Pamp and their antiallergic effects. RSC Advances. July 2017;7(54):34236-34243.
Keywords
