Epimagnolin B
Epimagnolin B is a bisepoxylignan isolated from Magnolia fargesii, with anti-inflammatory activity and antiallergic effects. Epimagnolin B inhibits NO production in LPS-activated microglia. Epimagnolin B exhibited antiallergic effects.
For research use only. We do not sell to patients.
- CAS No.: 1134188-26-3
- Formula: C23H28O7
- Molecular Weight:416.46
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| BV-2 | IC50 |
10.9 μM
Compound: 4
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Inhibition of NO production in LPS-stimulated mouse BV2 cells assessed as nitrite accumulation after 20 hrs by Griess reagent method
Inhibition of NO production in LPS-stimulated mouse BV2 cells assessed as nitrite accumulation after 20 hrs by Griess reagent method
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[PMID: 19110419] |
Epimagnolin B exhibits antiallergic effects without affecting the viability of BMMCs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1134188-26-3
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Molecular Weight 416.46
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Formula C23H28O7
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SMILES
COC1=C(OC)C(OC)=CC([C@@H]2[C@]3([H])[C@]([C@H](C4=CC(OC)=CC(OC)=C4)OC3)([H])CO2)=C1
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)