113731-96-7
Chemical Structure
Protein Kinase C (19-36)
- CAS No.: 113731-96-7
- Formula:C93H159N35O24
- Molecular Weight:2151.48
IUPAC Name: (6S,9S,12S,15S,18S,24S,27S,30S,33S,36S,39S,42S,45S,48S,51S,54S,57S)-45-((1H-imidazol-5-yl)methyl)-1,6-diamino-39,57-bis(2-amino-2-oxoethyl)-33-(3-amino-3-oxopropyl)-18,36,54-tris(4-aminobutyl)-9-benzyl-48-(2-carboxyethyl)-15,30-bis(3-guanidinopropyl)-1-imino-27-isobutyl-42,51-diisopropyl-12,24-dimethyl-7,10,13,16,19,22,25,28,31,34,37,40,43,46,49,52,55-heptadecaoxo-2,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,56-octadecaazaoctapentacontan-58-oic acid
SMILES: NC(C[C@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC1=CN=CN1)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC2=CC=CC=C2)NC([C@H](CCCNC(N)=N)N)=O)=O)C)=O)CCCNC(N)=N)=O)CCCCN)=O)=O)C)=O)CC(C)C)=O)CCCNC(N)=N)=O)CCC(N)=O)=O)CCCCN)=O)CC(N)=O)=O)C(C)C)=O)=O)CCC(O)=O)=O)C(C)C)=O)CCCCN)=O)C(O)=O)=O
Biological Activity: Protein Kinase C (19-36) is a pseudosubstrate peptide inhibitor of protein kinase C (PKC), with an IC50 of 0.18 μM. Protein Kinase C (19-36) markedly attenuated vascular hyperproliferation and hypertrophy as well as glucose-induced suppression of natriuretic peptide receptor response[1].
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Protein Kinase C (19-36) | 99.14% | Protein Kinase C (19-36) is a pseudosubstrate peptide inhibitor of protein kinase C (PKC), with an IC50 of 0.18 μM. Protein Kinase C (19-36) markedly attenuated vascular hyperproliferation and hypertrophy as well as glucose-induced suppression of natriuretic peptide receptor response. | ||||||||||||||||||||
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Keywords
