115406-23-0
Chemical Structure
SCH-39370
- CAS No.: 115406-23-0
- Formula:C22H26N2O6
- Molecular Weight:414.45
IUPAC Name: (S)-2-(((S)-1-(((S)-2-carboxy-2-hydroxyethyl)amino)-1-oxo-3-phenylpropan-2-yl)amino)-4-phenylbutanoic acid
InChIKey: QAQRHURCJWHRJU-FHWLQOOXSA-N
SMILES: OC([C@H](CCC1=CC=CC=C1)N[C@H](C(NC[C@H](O)C(O)=O)=O)CC2=CC=CC=C2)=O
Biological Activity: SCH-39370 is a potent and specific inhibitor of neutral metalloendopeptidase (NEP) from rabbit kidney with an IC50 value of 11.2 nM. SCH-39370 potentiates biological responses to atrial natriuretic factor and lowers blood pressure in desoxycorticosterone acetate-sodium hypertensive rats[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
SCH-39370 | SCH-39370 is a potent and specific inhibitor of neutral metalloendopeptidase (NEP) from rabbit kidney with an IC50 value of 11.2 nM. SCH-39370 potentiates biological responses to atrial natriuretic factor and lowers blood pressure in desoxycorticosterone acetate-sodium hypertensive rats. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Keywords
