115436-74-3
115436-74-3
Chemical Structure
Ipazilide fumarate
Synonym(s): Win 54177-4 fumarate
- CAS No.: 115436-74-3
- Formula:C28H34N4O5
- Molecular Weight:506.59
IUPAC Name: N-(3-(diethylamino)propyl)-2-(4,5-diphenyl-1H-pyrazol-1-yl)acetamide fumarate
InChIKey: KKMOBFCMCCFTDX-WLHGVMLRSA-N
SMILES: CCN(CC)CCCNC(CN1C(C2=CC=CC=C2)=C(C3=CC=CC=C3)C=N1)=O.O=C(O)/C=C/C(O)=O
Biological Activity: Ipazilide fumarate (Win 54177-4 fumarate) is an antiarrhythmic agent. Ipazilide fumarate reduces K+- depolarized tone. Ipazilide fumarate prolongs ventricular refractoriness and possesses antiectopic activity[1][2].
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Ipazilide fumarate | Ipazilide fumarate (Win 54177-4 fumarate) is an antiarrhythmic agent. Ipazilide fumarate reduces K+- depolarized tone. Ipazilide fumarate prolongs ventricular refractoriness and possesses antiectopic activity. | |||||||||||||||||||||
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References
- [1]. Greener Y, et al. Chronic (1-year) safety evaluation of ipazilide fumarate, an antiarrhythmic agent, administered orally to rats. Fundam Appl Toxicol. 1993 Feb;20(2):147-54. [Content Brief]
- [2]. Ezrin A M, et al. In vivo and in vitro effects of the novel antiarrhythmic ipazilide on cardiac and vascular smooth muscle function[J]. Drug development research, 1992, 27(2): 107-120.
Keywords
