117796-62-0
117796-62-0
Chemical Structure
Sch-40338
- CAS No.: 117796-62-0
- Formula:C20H22ClN3O
- Molecular Weight:355.86
IUPAC Name: 1-(4-(8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)piperazin-1-yl)ethan-1-one
InChIKey: AIESXMXVDNOKQF-UHFFFAOYSA-N
SMILES: CC(N1CCN(CC1)C2C3=CC=C(C=C3CCC4=CC=CN=C24)Cl)=O
Biological Activity: Sch-40338 is a dual antagonist of platelet-activating factor (PAF) and histamine with an IC50 of 0.59 μM (PAF-induced platelet aggregation) and a Ki of 5.4 μM (Histamine H₁ receptor binding). Sch-40338 can be used for the study of allergic disease[1].
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Sch-40338 | Sch-40338 is a dual antagonist of platelet-activating factor (PAF) and histamine with an IC50 of 0.59 μM (PAF-induced platelet aggregation) and a Ki of 5.4 μM (Histamine H₁ receptor binding). Sch-40338 can be used for the study of allergic disease. | |||||||||||||||||||||
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References
Keywords
