1185025-41-5
1185025-41-5
Chemical Structure
Carbamazepine 10,11 epoxide-d2
- CAS No.: 1185025-41-5
- Formula:C15H10D2N2O2
- Molecular Weight:254.28
IUPAC Name: 1a,10b-dihydro-6H-dibenzo[b,f]oxireno[2,3-d]azepine-1a,10b-d2-6-carboxamide
InChIKey: ZRWWEEVEIOGMMT-FLZZRPEZSA-N
SMILES: NC(N1C2=CC=CC=C2C3([2H])C(C4=CC=CC=C41)([2H])O3)=O
Biological Activity: Carbamazepine 10,11 epoxide-d2 is the deuterium labeled Carbamazepine 10,11 epoxide[1]. Carbamazepine 10,11-epoxide is an orally active metabolite of Carbamazepine (HY-B0246). Carbamazepine has anticonvulsant effect. Carbamazepine can be used for the research of seizures[2].
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Carbamazepine 10,11 epoxide-d2 | Carbamazepine 10,11 epoxide-d2 is the deuterium labeled Carbamazepine 10,11 epoxide. Carbamazepine 10,11-epoxide is an orally active metabolite of Carbamazepine (HY-B0246). Carbamazepine has anticonvulsant effect. Carbamazepine can be used for the research of seizures. | |||||||||||||||||||||
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Carbamazepine 10,11-epoxide (Standard) | 99.18% | Carbamazepine 10,11-epoxide (Standard) is the analytical standard of Carbamazepine 10,11-epoxide (HY-W013378). Carbamazepine 10,11-epoxide is a metabolite of Carbamazepine (HY-B0246). Carbamazepine 10,11-epoxide can be used to monitor for Carbamazepine. | ||||||||||||||||||||
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Carbamazepine 10,11 epoxide-d10 | 99.0% | Carbamazepine 10,11 epoxide-d10 is the deuterium labeled Carbamazepine 10,11 epoxide. | ||||||||||||||||||||
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Carbamazepine 10,11-epoxide | 99.14% | Carbamazepine 10,11-epoxide is a metabolite of Carbamazepine (HY-B0246). Carbamazepine 10,11-epoxide can be used to monitor for Carbamazepine. | ||||||||||||||||||||
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References
- [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
- [2]. T Tomson, et al. Single-dose kinetics and metabolism of carbamazepine-10,11-epoxide. Clin Pharmacol Ther. 1983 Jan;33(1):58-65. [Content Brief]
