1186430-60-3
1186430-60-3
Chemical Structure
Antihistamine-1
- CAS No.: 1186430-60-3
- Formula:C23H24FN5
- Molecular Weight:389.47
IUPAC Name: 1-(4-fluorobenzyl)-2-(4-(4-methyl-1H-pyrazol-1-yl)piperidin-1-yl)-1H-benzo[d]imidazole
InChIKey: YGQQBKYVKLZEMA-UHFFFAOYSA-N
SMILES: CC1=CN(C2CCN(C3=NC4=CC=CC=C4N3CC5=CC=C(F)C=C5)CC2)N=C1
Biological Activity: Antihistamine-1 is a H1-antihistamine (Ki=6.9 nM) with acceptable blood-brain barrier penetration and also an inhibitor of CYP2D6 and hERG channel with IC50s of 5.4 and 0.8 μM, respectively.
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Antihistamine-1 | 99.08% | Antihistamine-1 is a H1-antihistamine (Ki=6.9 nM) with acceptable blood-brain barrier penetration and also an inhibitor of CYP2D6 and hERG channel with IC50s of 5.4 and 0.8 μM, respectively. | ||||||||||||||||||||
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Antihistamine-1 (Standard) | ≥98% | Antihistamine-1 (Standard) is the analytical standard of Antihistamine-1 (HY-100238). This product is intended for research and analytical applications. Antihistamine-1 is a H1-antihistamine (Ki=6.9 nM) with acceptable blood-brain barrier penetration and also an inhibitor of CYP2D6 and hERG channel with IC50s of 5.4 and 0.8 μM, respectively. | ||||||||||||||||||||
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