1202759-32-7
1202759-32-7
Chemical Structure
CNX-774
- CAS No.: 1202759-32-7
- Formula:C26H22FN7O3
- Molecular Weight:499.50
IUPAC Name: 4-(4-((4-((3-acrylamidophenyl)amino)-5-fluoropyrimidin-2-yl)amino)phenoxy)-N-methylpicolinamide
InChIKey: VVLHQJDAUIPZFH-UHFFFAOYSA-N
SMILES: O=C(NC)C1=NC=CC(OC2=CC=C(NC3=NC=C(F)C(NC4=CC=CC(NC(C=C)=O)=C4)=N3)C=C2)=C1
Biological Activity: CNX-774 is an orally active, irreversible and selective BTK inhibitor, with an IC50 of < 1 nM. CNX-774 specifically targets Cysteine 481 of Btk for covalent modification[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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CNX-774 | 99.54% | CNX-774 is an orally active, irreversible and selective BTK inhibitor, with an IC50 of < 1 nM. CNX-774 specifically targets Cysteine 481 of Btk for covalent modification. | ||||||||||||||||||||
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References
Keywords
