120278-22-0
120278-22-0
Chemical Structure
Salvinolone
- CAS. Nr.: 120278-22-0
- Formula:C20H26O3
- Molecular Weight:314.42
IUPAC Name: 11,12-bis(4-hydroxyphenyl)-10,11-dihydro-5H-5,10-methanodibenzo[a,d][7]annulene-1,3,6,8-tetraol
InChIKey: NPADGWOASIJKSB-FQEVSTJZSA-N
SMILES: CC(C(C=C12)=C(O)C(O)=C2[C@@](C)(CCCC3(C)C)C3=CC1=O)C
Biological Activity: Salvinolone is active against methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococcus (VRE). Salvinolone shows cytotoxic activity with an IC50 of 47.6 μM against the HL-60 tumor cell line for 72 h[1][2].
| Art. -Nr. | Produktname | Reinheit | Beschreibung | Pricing | |||||||||||||||||||
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Salvinolone | 98.51% | Salvinolone is active against methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococcus (VRE). Salvinolone shows cytotoxic activity with an IC50 of 47.6 μM against the HL-60 tumor cell line for 72 h. | ||||||||||||||||||||
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References
- [1]. Mingfeng Xu, et al. Bioactive diterpenes from Clerodendrum kaichianum. Nat Prod Commun. 2011 Jan;6(1):3-5. [Content Brief]
- [2]. EnriqueAlvarez-Manzaneda, et al. First synthesis of picealactone C. A new route toward taxodione-related terpenoids from abietic acid. Tetrahedron Letters, Volume 48, Issue 6, 5 February 2007, Pages 989-992.
Keywords
