1207481-21-7
1207481-21-7
Chemical Structure
PF-46396
- CAS No.: 1207481-21-7
- Formula:C27H29F3N2O
- Molecular Weight:454.53
IUPAC Name: 1-(2-(4-(tert-butyl)phenyl)-2-((2,3-dihydro-1H-inden-2-yl)amino)ethyl)-3-(trifluoromethyl)pyridin-2(1H)-one
InChIKey: ARDZNPZYNMTXDH-UHFFFAOYSA-N
SMILES: O=C1C(C(F)(F)F)=CC=CN1CC(NC2CC3=C(C=CC=C3)C2)C4=CC=C(C(C)(C)C)C=C4
Biological Activity: PF-46396 is a potent HIV-1 inhibitor with an EC50 value of 0.206 µM. PF-46396 shows antiviral activity. PF-46396 inhibits the processing of capsid (CA)/spacer peptide 1 (SP1) (p25) Gag precursor proteins and blocks maturation of the viral core particle[1].
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PF-46396 | PF-46396 is a potent HIV-1 inhibitor with an EC50 value of 0.206 µM. PF-46396 shows antiviral activity. PF-46396 inhibits the processing of capsid (CA)/spacer peptide 1 (SP1) (p25) Gag precursor proteins and blocks maturation of the viral core particle. | |||||||||||||||||||||
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References
Keywords
