1216659-54-9
1216659-54-9
Chemical Structure
Ciprofloxacin-d8 hydrochloride
Synonym(s): Bay-09867-d8 hydrochloride
- CAS No.: 1216659-54-9
- Formula:C17H11D8ClFN3O3
- Molecular Weight:375.85
IUPAC Name: 1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl-2,2,3,3,5,5,6,6-d8)-1,4-dihydroquinoline-3-carboxylic acid hydrochloride
InChIKey: DIOIOSKKIYDRIQ-JCYLEXHWSA-N
SMILES: O=C1C2=CC(F)=C(N3C([2H])([2H])C([2H])([2H])NC([2H])([2H])C3([2H])[2H])C=C2N(C4CC4)C=C1C(O)=O.Cl
Biological Activity: Ciprofloxacin-d8 (hydrochloride) is the deuterium labeled Ciprofloxacin. Ciprofloxacin (Bay-09867) hydrochloride is a fluoroquinolone antibiotic, exhibiting potent antibacterial activity.
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Ciprofloxacin-d8 hydrochloride | 98.76% | Ciprofloxacin-d8 (hydrochloride) is the deuterium labeled Ciprofloxacin. Ciprofloxacin (Bay-09867) hydrochloride is a fluoroquinolone antibiotic, exhibiting potent antibacterial activity. | ||||||||||||||||||||
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Ciprofloxacin hydrochloride monohydrate (Standard) | 99.63% | Ciprofloxacin (hydrochloride monohydrate) (Standard) is the analytical standard of Ciprofloxacin (hydrochloride monohydrate). This product is intended for research and analytical applications. Ciprofloxacin (Bay-09867) hydrochloride monohydrate is a potent, orally active topoisomerase IV inhibitor. Ciprofloxacin hydrochloride monohydrate induces mitochondrial DNA and nuclear DNA damage and lead to mitochondrial dysfunction, ROS production. Ciprofloxacin hydrochloride monohydrate has anti-proliferative activity and induces apoptosis. Ciprofloxacin hydrochloride monohydrate is a fluoroquinolone antibiotic, exhibiting potent antibacterial activity. | ||||||||||||||||||||
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Ciprofloxacin-d8 hydrochloride monohydrate | Ciprofloxacin-d8 (hydrochloride monohydrate) is the deuterium labeled Ciprofloxacin (hydrochloride monohydrate). Ciprofloxacin hydrochloride is a fluoroquinolone antibiotic, exhibiting potent antibacterial activity. | |||||||||||||||||||||
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Ciprofloxacin hydrochloride monohydrate | 99.88% | Ciprofloxacin (Bay-09867) hydrochloride monohydrate is an orally active, blood-brain barrier permeable fluoroquinolone antibacterial agent. Ciprofloxacin hydrochloride monohydrate exerts bactericidal effects primarily by inhibiting topoisomerase II and IV. Ciprofloxacin hydrochloride monohydrate inhibits the proliferation of human dental pulp stem cells and chondrocytes from young rats, and also activates the Akt signaling pathway and upregulates markers such as β-catenin and Nanog to maintain the morphological characteristics of stem cells. Ciprofloxacin hydrochloride monohydrate induces significant neurotoxicity and tissue damage, including reducing serotonin and glutathione levels in the brain, inducing oxidative stress and depression-like behaviors, and causing articular cartilage damage. Ciprofloxacin hydrochloride monohydrate can be applied to research related to infections of necrotic young permanent teeth and neurotoxicity. | ||||||||||||||||||||
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