1217661-20-5
1217661-20-5
Chemical Structure
Amprenavir-d4
- CAS No.: 1217661-20-5
- Formula:C25H31D4N3O6S
- Molecular Weight:509.65
IUPAC Name: (S)-tetrahydrofuran-3-yl-2,2,5,5-d4 ((2S,3R)-4-((4-amino-N-isobutylphenyl)sulfonamido)-3-hydroxy-1-phenylbutan-2-yl)carbamate
InChIKey: YMARZQAQMVYCKC-OZXFPYGFSA-N
SMILES: O=S(N(CC(C)C)C[C@@H](O)[C@@H](NC(O[C@H]1CC([2H])([2H])OC1([2H])[2H])=O)CC2=CC=CC=C2)(C3=CC=C(C=C3)N)=O
Biological Activity: Amprenavir-d4 is the deuterium labeled Amprenavir. Amprenavir (VX-478) is a HIV protease inhibitor (Ki=0.6 nM) used to treat HIV infection. Amprenavir is also a SARS-CoV 3CLpro inhibitor with an IC50 of 1.09 μM[1][2].
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Amprenavir-d4 | Amprenavir-d4 is the deuterium labeled Amprenavir. Amprenavir (VX-478) is a HIV protease inhibitor (Ki=0.6 nM) used to treat HIV infection. Amprenavir is also a SARS-CoV 3CLpro inhibitor with an IC50 of 1.09 μM. | |||||||||||||||||||||
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Amprenavir (Standard) | ≥98% | Amprenavir (Standard) is the analytical standard of Amprenavir. This product is intended for research and analytical applications. Amprenavir (VX-478) is a HIV protease inhibitor (Ki=0.6 nM) used to treat HIV infection. Amprenavir is also a SARS-CoV 3CLpro inhibitor with an IC50 of 1.09 μM. | ||||||||||||||||||||
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Amprenavir-d4-1 | Amprenavir-d4-1 is deuterium labeled Amprenavir. Amprenavir (VX-478) is a HIV protease inhibitor (Ki=0.6 nM) used to treat HIV infection. Amprenavir is also a SARS-CoV 3CLpro inhibitor with an IC50 of 1.09 μM. | |||||||||||||||||||||
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Amprenavir-13C6 | Amprenavir-13C6 (VX-478-13C6) is 13C labeled Amprenavir. Amprenavir (VX-478) is a HIV protease inhibitor (Ki=0.6 nM) used to treat HIV infection. Amprenavir is also a SARS-CoV 3CLpro inhibitor with an IC50 of 1.09 μM. | |||||||||||||||||||||
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Amprenavir | 99.55% | Amprenavir (VX-478) is a HIV protease inhibitor (Ki=0.6 nM) used to treat HIV infection. Amprenavir is also a SARS-CoV 3CLpro inhibitor with an IC50 of 1.09 μM. | ||||||||||||||||||||
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References
