1221971-47-6
1221971-47-6
Chemical Structure
PF-9184
- CAS No.: 1221971-47-6
- Formula:C21H14Cl2N2O4S
- Molecular Weight:461.32
IUPAC Name: N-(3',4'-dichloro-[1,1'-biphenyl]-4-yl)-4-hydroxy-2H-benzo[e][1,2]thiazine-3-carboxamide 1,1-dioxide
InChIKey: VGACSWBJQLLJFB-UHFFFAOYSA-N
SMILES: O=C(C1=C(O)C2=CC=CC=C2S(N1)(=O)=O)NC3=CC=C(C4=CC=C(Cl)C(Cl)=C4)C=C3
Biological Activity: PF-9184 is a potent and highly selective inhibitor of human microsomal prostaglandin E synthase-1 (mPGES-1), with an IC50 of 16.5 nM. PF-9184 inhibits IL-1β-induced PGE2 synthesis in vitro[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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PF-9184 | 98.10% | PF-9184 is a potent and highly selective inhibitor of human microsomal prostaglandin E synthase-1 (mPGES-1), with an IC50 of 16.5 nM. PF-9184 inhibits IL-1β-induced PGE2 synthesis in vitro. | ||||||||||||||||||||
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References
Keywords
