122654-28-8
122654-28-8
Chemical Structure
3’-Deoxy-3’-fluoro-N6,N6-dimethyladenosine
- CAS No.: 122654-28-8
- Formula:C12H16FN5O3
- Molecular Weight:297.29
IUPAC Name: (2R,3S,4S,5R)-2-(6-(dimethylamino)-9H-purin-9-yl)-4-fluoro-5-(hydroxymethyl)tetrahydrofuran-3-ol
InChIKey: ADCDWMXLHKTMSO-GRIPGOBMSA-N
SMILES: F[C@H]1[C@@H](O)[C@H](N2C(N=CN=C3N(C)C)=C3N=C2)O[C@@H]1CO
Biological Activity: 3’-Deoxy-3’-fluoro-N6,N6-dimethyladenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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3’-Deoxy-3’-fluoro-N6,N6-dimethyladenosine | 3’-Deoxy-3’-fluoro-N6,N6-dimethyladenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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