122654-30-2
122654-30-2
Chemical Structure
2-Chloro-3’-deoxy-3’-fluoroadenosine
- CAS No.: 122654-30-2
- Formula:C10H11ClFN5O3
- Molecular Weight:303.68
IUPAC Name: (2R,3S,4S,5R)-2-(6-amino-2-chloro-9H-purin-9-yl)-4-fluoro-5-(hydroxymethyl)tetrahydrofuran-3-ol
InChIKey: IRHXEJNSFOBHLE-DXTOWSMRSA-N
SMILES: NC1=C2C(N([C@@H]3O[C@H](CO)[C@@H](F)[C@H]3O)C=N2)=NC(Cl)=N1
Biological Activity: 2-Chloro-3’-deoxy-3’-fluoroadenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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2-Chloro-3’-deoxy-3’-fluoroadenosine | 2-Chloro-3’-deoxy-3’-fluoroadenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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References
Keywords
