1227627-77-1
Chemical Structure
TMTP1
- CAS No.: 1227627-77-1
- Formula:C25H46N10O8
- Molecular Weight:614.69
InChIKey: OYFUDXGEBZIUQX-FLKCQLHMSA-N
SMILES: O=C(N[C@@H](C(C)C)C(N[C@@H](C(C)C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCC(N)=O)C(O)=O)=O)=O)=O)[C@H](CC(N)=O)N
Biological Activity: TMTP1 is a five-amino acid (NVVRQ) tumor-homing peptide. TMTP1 slows the growth of tumor cells. TMTP1 serves as a diagnostic marker for hematological malignancies and acts as an anticancer drug carrier to enhance the cellular uptake rate of nanocarriers in tumor tissues. TMTP1 is applicable to research related to hematological malignancies, lymphoma, chronic myeloid leukemia, cervical cancer, and ovarian cancer[1][2][3].
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TMTP1 | TMTP1 is a five-amino acid (NVVRQ) tumor-homing peptide. TMTP1 slows the growth of tumor cells. TMTP1 serves as a diagnostic marker for hematological malignancies and acts as an anticancer drug carrier to enhance the cellular uptake rate of nanocarriers in tumor tissues. TMTP1 is applicable to research related to hematological malignancies, lymphoma, chronic myeloid leukemia, cervical cancer, and ovarian cancer. | |||||||||||||||||||||
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- [1]. Xiao M, et al.. TMTP1, a novel tumor-homing peptide, specifically targets hematological malignancies and their metastases. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban. 2011 Oct;31(5):608. [Content Brief]
- [2]. Xu H, et al.. TMTP1-modified nanocarrier boosts cervical cancer immunotherapy by eliciting pyroptosis. Theranostics. 2025;15(11):5420-5439. [Content Brief]
- [3]. Zhou Y, et al.. Tumor targeting peptide TMTP1 modified Antigen capture Nano-vaccine combined with chemotherapy and PD-L1 blockade effectively inhibits growth of ovarian cancer. Journal of nanobiotechnology. 2024 Aug 13;22(1):483. [Content Brief]
Keywords
