1235033-39-2
1235033-39-2
Chemical Structure
BCL-XL-IN-4
- CAS No.: 1235033-39-2
- Formula:C34H26N8O4S2
- Molecular Weight:674.75
IUPAC Name: 5-(2-(4-(1H-pyrazolo[3,4-d]pyrimidin-1-yl)phenoxy)ethyl)-2-(8-(benzo[d]thiazol-2-ylcarbamoyl)-3,4-dihydroisoquinolin-2(1H)-yl)thiazole-4-carboxylic acid
InChIKey: AUSCDMYCFSINPV-UHFFFAOYSA-N
SMILES: O=C(C1=C(CCOC2=CC=C(N3N=CC4=CN=CN=C43)C=C2)SC(N5CC6=C(C=CC=C6C(NC7=NC8=CC=CC=C8S7)=O)CC5)=N1)O
Biological Activity: BCL-XL-IN-4 (compound 10) is a potent and selective BCL-XL inhibitor with Ki values of 0.042, 170 nM for BCL-XL, BCL-2, respectively. BCL-XL-IN-4 shows cytotoxicity[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
BCL-XL-IN-4 | BCL-XL-IN-4 (compound 10) is a potent and selective BCL-XL inhibitor with Ki values of 0.042, 170 nM for BCL-XL, BCL-2, respectively. BCL-XL-IN-4 shows cytotoxicity. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
Keywords
