1235445-80-3
1235445-80-3
Chemical Structure
(S)-Indacaterol
- CAS No.: 1235445-80-3
- Formula:C24H28N2O3
- Molecular Weight:392.49
IUPAC Name: (S)-5-(2-((5,6-diethyl-2,3-dihydro-1H-inden-2-yl)amino)-1-hydroxyethyl)-8-hydroxyquinolin-2(1H)-one
InChIKey: QZZUEBNBZAPZLX-JOCHJYFZSA-N
SMILES: O=C1NC2=C(C([C@H](O)CNC3CC4=C(C=C(CC)C(CC)=C4)C3)=CC=C2O)C=C1
Biological Activity: (S)-Indacaterol is the S-enantiomer of Indacaterol (HY-14299). Indacaterol is an orally active ultra-long-acting β2 adrenergic receptor (ADRB2) agonist[1][2].
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(S)-Indacaterol | (S)-Indacaterol is the S-enantiomer of Indacaterol (HY-14299). Indacaterol is an orally active ultra-long-acting β2 adrenergic receptor (ADRB2) agonist. | |||||||||||||||||||||
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References
- [1]. Jadwiga A Wedzicha, et al. Indacaterol-Glycopyrronium versus Salmeterol-Fluticasone for COPD. N Engl J Med. 2016 Jun 9;374(23):2222-34. [Content Brief]
- [2]. Lee SU, et al. Indacaterol inhibits tumor cell invasiveness and MMP-9 expression by suppressing IKK/NF-κB activation. Mol Cells. 2014 Aug;37(8):585-91. [Content Brief]
Keywords
