1244640-48-9
Chemical Structure
VU 0364739 hydrochloride
- CAS No.: 1244640-48-9
- Formula:C26H28ClFN4O2
- Molecular Weight:482.98
IUPAC Name: N-(2-(1-(3-fluorophenyl)-4-oxo-1,3,8-triazaspiro[4.5]decan-8-yl)ethyl)-2-naphthamide hydrochloride
InChIKey: RYLAMDMOILNBKN-UHFFFAOYSA-N
SMILES: O=C(C1=CC=C2C=CC=CC2=C1)NCCN(CC3)CCC3(N(C4=CC=CC(F)=C4)CN5)C5=O.[H]Cl
Biological Activity: VU 0364739 hydrochloride is a highly selective phospholipase D2 (PLD2) inhibitor with IC50s of 20 and 1500 nM for PLD2 and PLD1, respectively. VU 0364739 hydrochloride induces apoptosis and it can be used for cancer research[1].
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VU 0364739 hydrochloride | VU 0364739 hydrochloride is a highly selective phospholipase D2 (PLD2) inhibitor with IC50s of 20 and 1500 nM for PLD2 and PLD1, respectively. VU 0364739 hydrochloride induces apoptosis and it can be used for cancer research. | |||||||||||||||||||||
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Keywords