1246814-59-4
1246814-59-4
Chemical Structure
PD-166285-d4
- CAS No.: 1246814-59-4
- Formula:C26H23D4Cl2N5O2
- Molecular Weight:589.38
IUPAC Name: 6-(2,6-dichlorophenyl)-2-((4-(2-(diethylamino)ethoxy-1,1,2,2-d4)phenyl)amino)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one
InChIKey: IFPPYSWJNWHOLQ-RYIWKTDQSA-N
SMILES: O=C1C(=CC=2C(N1C)=NC(NC3=CC=C(OC(C(N(CC)CC)([2H])[2H])([2H])[2H])C=C3)=NC2)C4=C(Cl)C=CC=C4Cl
Biological Activity: PD-166285-d4 is the deuterium labeled PD-166285[1].
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PD-166285-d4 | PD-166285-d4 is the deuterium labeled PD-166285. | |||||||||||||||||||||
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PD0166285 dihydrochloride | PD0166285 dihydrochloride, a substrate of P-gp, is a WEE1 inhibitor and a weak Myt1 inhibitor with IC50 values of 24 and 72 nM, respectively. PD0166285 dihydrochloride exhibits an IC50 of 3.433 μM for Chk1. | |||||||||||||||||||||
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References
