125399-82-8
Chemical Structure
Altemicidin
Synonym(s): (-)-Altemicidin
- CAS No.: 125399-82-8
- Formula:C13H20N4O7S
- Molecular Weight:376.39
IUPAC Name: (4aR,6S,7R,7aS)-4-carbamoyl-6-hydroxy-2-methyl-7-(2-sulfamoylacetamido)-2,4a,5,6,7,7a-hexahydro-1H-cyclopenta[c]pyridine-7-carboxylic acid
InChIKey: VZRFZUPFQKSXPV-VPFIQFBESA-N
SMILES: O=C(C[S](N)(=O)=O)N[C@@]1([C@@](CN2C)([H])[C@@](C(C(N)=O)=C2)([H])C[C@@H]1O)C(O)=O
Biological Activity: Altemicidin is a monoterpene alkaloid originally isolated from S. sioyaensis with acaricidal and anticancer activities. It is acaricidal to two-spotted spider mites (T. urticae) in a greenhouse pot test at concentrations of 10 and 100 ppm. Altemicidin inhibits the growth of murine L1210 lymphocytic leukemia and IMC carcinoma cells (IC50s=0.84 and 0.82 μg/mL, respectively). It is toxic to mice with an LD50 value of 0.3 mg/kg.
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Altemicidin | Altemicidin is a monoterpene alkaloid originally isolated from S. sioyaensis with acaricidal and anticancer activities. It is acaricidal to two-spotted spider mites (T. urticae) in a greenhouse pot test at concentrations of 10 and 100 ppm. Altemicidin inhibits the growth of murine L1210 lymphocytic leukemia and IMC carcinoma cells (IC50s=0.84 and 0.82 μg/mL, respectively). It is toxic to mice with an LD50 value of 0.3 mg/kg. | |||||||||||||||||||||
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Keywords
