1255942-08-5
1255942-08-5
Chemical Structure
DBCO-NHCO-PEG4-amine
- CAS No.: 1255942-08-5
- Formula:C29H37N3O6
- Molecular Weight:523.62
InChIKey: KTIOBJVNCOFWCL-UHFFFAOYSA-N
SMILES: O=C(N1CC2=C(C#CC3=C1C=CC=C3)C=CC=C2)CCNC(CCOCCOCCOCCOCCN)=O
Biological Activity: DBCO-NHCO-PEG4-amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. DBCO-NHCO-PEG4-amine is a cleavable ADC linker used to conjugate MMAE (HY-15162) and antibody (e.g., DBCO-VCpAB MMAE and DBCO-TRX MMAE with EC50s of 280 nM and 22 nM in SKBR3 cells, respectively)[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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DBCO-NHCO-PEG4-amine | 96.37% | DBCO-NHCO-PEG4-amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. DBCO-NHCO-PEG4-amine is a cleavable ADC linker used to conjugate MMAE (HY-15162) and antibody (e.g., DBCO-VCpAB MMAE and DBCO-TRX MMAE with EC50s of 280 nM and 22 nM in SKBR3 cells, respectively). | ||||||||||||||||||||
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References
Keywords
