1261396-65-9
Chemical Structure
Oxcarbazepine-d8
Synonym(s): GP 47680-d8
- CAS No.: 1261396-65-9
- Formula:C15H4D8N2O2
- Molecular Weight:260.32
IUPAC Name: 10-oxo-10,11-dihydro-5H-dibenzo[b,f]azepine-2,3,4,6,7,8,11,11-d8-5-carboxamide
InChIKey: CTRLABGOLIVAIY-UYHQKSDVSA-N
SMILES: NC(N1C2=C([2H])C([2H])=C([2H])C=C2C(C([2H])([2H])C3=CC([2H])=C([2H])C([2H])=C31)=O)=O
Biological Activity: Oxcarbazepine-d8-1 is a deuterium of Oxcarbazepine. Oxcarbazepine is a sodium channel blocker[1]. Oxcarbazepine significantly inhibits glioblastoma cell growth and induces apoptosis or G2/M arrest in glioblastoma cell lines[2]. Oxcarbazepine-d8-1 has anti-cancer and anticonvulsant effects[2].
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Oxcarbazepine-d8 | Oxcarbazepine-d8-1 is a deuterium of Oxcarbazepine. Oxcarbazepine is a sodium channel blocker. Oxcarbazepine significantly inhibits glioblastoma cell growth and induces apoptosis or G2/M arrest in glioblastoma cell lines. Oxcarbazepine-d8-1 has anti-cancer and anticonvulsant effects. | |||||||||||||||||||||
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Oxcarbazepine (Standard) | 99.88% | Oxcarbazepine (Standard) is the analytical standard of Oxcarbazepine. This product is intended for research and analytical applications. Oxcarbazepine is a sodium channel blocker. Oxcarbazepine significantly inhibits glioblastoma cell growth and induces apoptosis or G2/M arrest in glioblastoma cell lines. Anti-cancer and anticonvulsant effects. | ||||||||||||||||||||
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Oxcarbazepine-d10 | Oxcarbazepine-d10 (GP 47680-d10) is deuterium labeled Oxcarbazepine. Oxcarbazepine is a sodium channel blocker. Oxcarbazepine significantly inhibits glioblastoma cell growth and induces apoptosis or G2/M arrest in glioblastoma cell lines. Anti-cancer and anticonvulsant effects. | |||||||||||||||||||||
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Oxcarbazepine-d4 | Oxcarbazepine-d4 (GP 47680-D4) is the deuterium labeled Oxcarbazepine. Oxcarbazepine is a sodium channel blocker. Oxcarbazepine significantly inhibits glioblastoma cell growth and induces apoptosis or G2/M arrest in glioblastoma cell lines. Anti-cancer and anticonvulsant effects. | |||||||||||||||||||||
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Oxcarbazepine-d4-1 | Oxcarbazepine-d4-1 is deuterium labeled Oxcarbazepine. Oxcarbazepine is a sodium channel blocker. Oxcarbazepine significantly inhibits glioblastoma cell growth and induces apoptosis or G2/M arrest in glioblastoma cell lines. Anti-cancer and anticonvulsant effects. | |||||||||||||||||||||
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Oxcarbazepine | 99.90% | Oxcarbazepine is a sodium channel blocker. Oxcarbazepine significantly inhibits glioblastoma cell growth and induces apoptosis or G2/M arrest in glioblastoma cell lines. Anti-cancer and anticonvulsant effects. | ||||||||||||||||||||
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- [1]. Ashley M Thomas, et al. Old Friends With New Faces: Are Sodium Channel Blockers the Future of Adjunct Pain Medication Management?J Pain. 2018 Jan;19(1):1-9. [Content Brief]
- [2]. Ching-Yi Lee,et al. The effects of antiepileptic drugs on the growth of glioblastoma cell lines. J Neurooncol. 2016 May;127(3):445-53. [Content Brief]
