1269190-98-8
Chemical Structure
yGsy2p-IN-H23
- CAS No.: 1269190-98-8
- Formula:C23H27N3O2
- Molecular Weight:377.48
IUPAC Name: 2-methoxy-4-(1-(2-(1-methylpyrrolidin-2-yl)ethyl)-4-phenyl-1H-imidazol-5-yl)phenol
InChIKey: YGPHAIXUDLLWHC-UHFFFAOYSA-N
SMILES: OC1=CC=C(C2=C(C3=CC=CC=C3)N=CN2CCC4N(C)CCC4)C=C1OC
Biological Activity: yGsy2p-IN-H23 is a potent and first-in-class inhibitor for yeast glycogen synthase 2 (yGsy2p) with an IC50 of 875 μM for human glycogen synthase 1 (hGYS1). yGsy2p-IN-H23 bounds within the uridine diphosphate glucose binding pocket of yGsy2p. yGsy2p-IN-H23 is used for the research of glycogen storage diseases (GSDs)[1].
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yGsy2p-IN-H23 | 99.91% | yGsy2p-IN-H23 is a potent and first-in-class inhibitor for yeast glycogen synthase 2 (yGsy2p) with an IC50 of 875 μM for human glycogen synthase 1 (hGYS1). yGsy2p-IN-H23 bounds within the uridine diphosphate glucose binding pocket of yGsy2p. yGsy2p-IN-H23 is used for the research of glycogen storage diseases (GSDs). | ||||||||||||||||||||
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Keywords
