1279033-22-5
1279033-22-5
Chemical Structure
Griseofulvin-d3
- CAS No.: 1279033-22-5
- Formula:C17H14D3ClO6
- Molecular Weight:355.78
IUPAC Name: (2S,6'R)-7-chloro-4,6-dimethoxy-2'-(methoxy-d3)-6'-methyl-3H-spiro[benzofuran-2,1'-cyclohexan]-2'-ene-3,4'-dione
InChIKey: DDUHZTYCFQRHIY-BCBJJHLGSA-N
SMILES: O=C1[C@]2(C(OC([2H])([2H])[2H])=CC(C[C@H]2C)=O)OC3=C(Cl)C(OC)=CC(OC)=C31
Biological Activity: Griseofulvin-d3 is the deuterium labeled Griseofulvin. Griseofulvin (Gris-PEG) is a spirocyclic fungal natural product used in treatment of fungal dermatophytes; Antifungal agent[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Griseofulvin-d3 | Griseofulvin-d3 is the deuterium labeled Griseofulvin. Griseofulvin (Gris-PEG) is a spirocyclic fungal natural product used in treatment of fungal dermatophytes; Antifungal agent. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Griseofulvin (Standard) | 98.85% | Griseofulvin (Standard) is the analytical standard of Griseofulvin. This product is intended for research and analytical applications. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Griseofulvin-13C,d3 | Griseofulvin-13C,d3 is the 13C- and deuterium labeled Griseofulvin. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Griseofulvin | 99.07% | Griseofulvin is an orally active antifungal antibiotic with antitumor activity. Griseofulvin induces apoptosis and G2/M cell cycle arrest in cancer cells. Griseofulvin also has cardiovascular modulatory activity, reducing angina pectoris, relieving hand artery spasm associated with onychomycosis, and peripheral vascular diseases such as shoulder-hand syndrome. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
- [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
- [2]. Brilhante RSN, et al. In vitro activity of azole derivatives and griseofulvin against planktonic and biofilm growth of clinical isolates of dermatophytes. Mycoses. 2018 Jul;61(7):449-454. [Content Brief]
