129414-88-6
129414-88-6
Chemical Structure
Kribb3
- CAS No.: 129414-88-6
- Formula:C19H19NO4
- Molecular Weight:325.36
IUPAC Name: 4-ethyl-5-methoxy-2-(4-(4-methoxyphenyl)isoxazol-5-yl)phenol
InChIKey: BNBHIGLOMVMJDB-UHFFFAOYSA-N
SMILES: OC1=CC(OC)=C(C=C1C2=C(C=NO2)C3=CC=C(C=C3)OC)CC
Biological Activity: Kribb3 is an inhibitor for microtubule. KRIBB3 inhibits the proliferation of cancer cells with GI50 of 0.2-2.5 μM, arrests cell cycle at G2/M phase, and induces apoptosis in HCT-116. Kribb3 exhibits antitumor activity in mouse models[1].
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Kribb3 | Kribb3 is an inhibitor for microtubule. KRIBB3 inhibits the proliferation of cancer cells with GI50 of 0.2-2.5 μM, arrests cell cycle at G2/M phase, and induces apoptosis in HCT-116. Kribb3 exhibits antitumor activity in mouse models. | |||||||||||||||||||||
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References
Keywords
