1315538-79-4
1315538-79-4
Chemical Structure
PI3Kγ inhibitor 2
- CAS No.: 1315538-79-4
- Formula:C20H18F3N5O3
- Molecular Weight:433.38
IUPAC Name: (R)-2-(5,6-dimethoxypyridin-3-yl)-7-methyl-6-(1-(2,2,2-trifluoroethyl)-1H-pyrazol-4-yl)-6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-5-one
InChIKey: DREWJJJKWOJZQM-LLVKDONJSA-N
SMILES: O=C1N(C2=CN(CC(F)(F)F)N=C2)[C@H](C)C3=NC(C4=CC(OC)=C(OC)N=C4)=CC=C31
Biological Activity: PI3Kγ inhibitor 2 (Compound 16) is an orally bioavailable, CNS-penetrant, isoform selective PI3Kγ inhibitor with a Ki of 4 nM[1].
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PI3Kγ inhibitor 2 | PI3Kγ inhibitor 2 (Compound 16) is an orally bioavailable, CNS-penetrant, isoform selective PI3Kγ inhibitor with a Ki of 4 nM. | |||||||||||||||||||||
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References
Keywords
