131983-72-7
Chemical Structure
Triticonazole
- CAS No.: 131983-72-7
- Formula:C17H20ClN3O
- Molecular Weight:317.81
IUPAC Name: (Z)-1-((1H-1,2,4-triazol-1-yl)methyl)-5-(4-chlorobenzylidene)-2,2-dimethylcyclopentan-1-ol
InChIKey: PPDBOQMNKNNODG-ZROIWOOFSA-N
SMILES: OC1(CN2N=CN=C2)C(C)(C)CC/C1=C/C3=CC=C(Cl)C=C3
Biological Activity: Triticonazole is an orally active triazole fungicide and androgen receptor antagonist. Triticonazole inhibits testosterone-induced androgen receptor activation and reduces basal testosterone secretion. Prenatal exposure to Triticonazole causes shortened anogenital distance in male rat fetuses and induces organ-specific histopathological changes in pigs. Triticonazole can be used for detoxification of seeds contaminated with fungal pathogens, but there is a risk of animal poisoning if the treated seeds are used as animal feed[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Triticonazole | 95.73% | Triticonazole is an orally active triazole fungicide and androgen receptor antagonist. Triticonazole inhibits testosterone-induced androgen receptor activation and reduces basal testosterone secretion. Prenatal exposure to Triticonazole causes shortened anogenital distance in male rat fetuses and induces organ-specific histopathological changes in pigs. Triticonazole can be used for detoxification of seeds contaminated with fungal pathogens, but there is a risk of animal poisoning if the treated seeds are used as animal feed. | ||||||||||||||||||||
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Triticonazole (Standard) | ≥98% | Triticonazole (Standard) is the analytical standard of Triticonazole. This product is intended for research and analytical applications. Triticonazole is a triazole pesticide. Triticonazole is an azole fungicide and shows endocrine disrupting activities. | ||||||||||||||||||||
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References
- [1]. Draskau MK, et al. In vitro and in vivo endocrine disrupting effects of the azole fungicides triticonazole and flusilazole. Environ Pollut. 2019;255(Pt 2):113309. [Content Brief]
- [2]. Roelofs MJE, et al. Conazole fungicides inhibit Leydig cell testosterone secretion and androgen receptor activation in vitro. Toxicol Rep. 2014;1:271-283. Published 2014 May 22. [Content Brief]
- [3]. Binev R, et al. Pathomorphological studies following experimental acute intoxication with the triazole fungicide triticonazole in pigs[J]. Bulgarian Journal of Veterinary Medicine, 2005, 8(3): 193-198.
