133718-30-6
133718-30-6
Chemical Structure
R 80123
- CAS No.: 133718-30-6
- Formula:C26H29N5O3
- Molecular Weight:459.54
IUPAC Name: (Z)-N-cyclohexyl-N-methyl-2-((((2-oxo-1,2,3,5-tetrahydroimidazo[2,1-b]quinazolin-7-yl)(phenyl)methylene)amino)oxy)acetamide
InChIKey: VHDUUXNHZLBGHQ-GNVQSUKOSA-N
SMILES: O=C(N(C1CCCCC1)C)CO/N=C(C2=CC=CC=C2)\C3=CC4=C(N=C(NC(C5)=O)N5C4)C=C3
Biological Activity:
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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R 80123 | R 80123 is the Z-isomer of R 79595, is also a highly selective phosphodiesterase inhibitor. | |||||||||||||||||||||
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References
- Vandeplassche GM et al. Comparative effects of R 80122, enoximone, and milrinone on left ventricular phosphodiesterase isoenzymes in vitro and on contractility of normal and stunned myocardium in vivo in dogs. J Cardiovasc Pharmacol. 1992 May;19(5):714-22. https://www.ncbi.nlm.nih.gov/pubmed/ 1381769 [Content Brief]
- Schneider J et al. Cardiac effects of R 79595 and its isomers (R 80122 and R 80123) in an acute heart failure model. A new class of cardiotonic agents with highly selective phosphodiesterase III inhibitory properties. Naunyn Schmiedebergs Arch Pharmacol. 1992 Nov;346(5):563-72. [Content Brief]
- Vandeplassche GM et al. Comparative effects of R 80122, enoximone, and milrinone on left ventricular phosphodiesterase isoenzymes in vitro and on contractility of normal and stunned myocardium in vivo in dogs. J Cardiovasc Pharmacol. 1992 May;19(5):714-22. [Content Brief]
Keywords
