1338494-49-7
1338494-49-7
Chemical Structure
KT53
- CAS No.: 1338494-49-7
- Formula:C21H23ClFN3O2
- Molecular Weight:403.88
InChIKey: HHYJEFITGKRTJS-UHFFFAOYSA-N
SMILES: O=C(C(N(C1=CC(F)=CC=C1)C(CCl)=O)C2=NC=CC=C2)NC3CCCCC3
Biological Activity: KT53 is a highly active, selective, and cell penetrable GSTO1 inhibitor. KT53 can effectively inhibit GSTO1 activity in MDA-MB-435 (IC50 = 35 nM) cells. KT53 significantly enhances the killing effect of cisplatin (HY-17394) on MDA-MB-435 cancer cells. KT53 can be used for cancer research[1].
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KT53 | KT53 is a highly active, selective, and cell penetrable GSTO1 inhibitor. KT53 can effectively inhibit GSTO1 activity in MDA-MB-435 (IC50 = 35 nM) cells. KT53 significantly enhances the killing effect of cisplatin (HY-17394) on MDA-MB-435 cancer cells. KT53 can be used for cancer research. | |||||||||||||||||||||
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References
Keywords
