134431-49-5
Chemical Structure
KRN-2391
- CAS No.: 134431-49-5
- Formula:C10H13N5O6S
- Molecular Weight:331.31
IUPAC Name: (E)-2-((cyanamido(pyridin-3-yl)methylene)amino)ethyl nitrate methanesulfonate
InChIKey: BIBJJSCMCXFMML-UHFFFAOYSA-N
SMILES: O=[N+](OCC/N=C(C1=CC=CN=C1)/NC#N)[O-].CS(=O)(O)=O
Biological Activity: KRN-2391 is a KATP channel opener with NO donor properties. KRN-2391 exerts dual inhibitory effects on overactive bladder (OAB) by activating KATP channels (causing cellular hyperpolarization and bladder smooth muscle relaxation) and releasing NO (enhancing relaxation via cGMP pathways). KRN-2391 is promising for research of OAB[1].
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KRN-2391 | KRN-2391 is a KATP channel opener with NO donor properties. KRN-2391 exerts dual inhibitory effects on overactive bladder (OAB) by activating KATP channels (causing cellular hyperpolarization and bladder smooth muscle relaxation) and releasing NO (enhancing relaxation via cGMP pathways). KRN-2391 is promising for research of OAB. | |||||||||||||||||||||
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Keywords
