135015-84-8
135015-84-8
Chemical Structure
ICI-D 8731
Synonym(s): ZD-8731
- CAS No.: 135015-84-8
- Formula:C25H22ClN5O
- Molecular Weight:443.93
IUPAC Name: 4-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methoxy)-2-ethylquinoline hydrochloride
InChIKey: UDVVSNKCOWXHSG-UHFFFAOYSA-N
SMILES: CCC1=NC2=CC=CC=C2C(OCC3=CC=C(C=C3)C4=CC=CC=C4C5=NN=NN5)=C1.Cl
Biological Activity: ICI-D 8731 (compound 5g) is a angiotensin II receptor antagonist with the IC50 of 0.031 μM. ICI-D 8731 shows a rapid and sustained lowering of blood pressure in a renal hypertensive rat model[1].
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ICI-D 8731 | ICI-D 8731 (compound 5g) is a angiotensin II receptor antagonist with the IC50 of 0.031 μM. ICI-D 8731 shows a rapid and sustained lowering of blood pressure in a renal hypertensive rat model. | |||||||||||||||||||||
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References
Keywords
