135123-34-1
135123-34-1
Chemical Structure
2’-Deoxy-2’-fluoro-5-methyl-4’-thio-β-D-arabino uridine
- CAS No.: 135123-34-1
- Formula:C10H13FN2O4S
- Molecular Weight:276.28
IUPAC Name: 1-((2R,3S,4S,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrothiophen-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione
InChIKey: RCDAZGNPWLZONT-JVZYCSMKSA-N
SMILES: O[C@H]1[C@H](F)[C@H](N2C(NC(C(C)=C2)=O)=O)S[C@@H]1CO
Biological Activity: 2’-Deoxy-2’-fluoro-5-methyl-4’-thio-β-D-arabino uridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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2’-Deoxy-2’-fluoro-5-methyl-4’-thio-β-D-arabino uridine | 2’-Deoxy-2’-fluoro-5-methyl-4’-thio-β-D-arabino uridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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